|
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
PP2Calpha
PP2C-ALPHA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
· 
WB
Western blot
analysis using PPM1A antibody against HepG2(1) cell lysate.
· 
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
PP2Calpha
PP2C-ALPHA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
WB
Western blot
analysis using PPM1A antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
PP2Calpha
PP2C-ALPHA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
WB
Western blot
analysis using PPM1A antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
PP2Calpha
PP2C-ALPHA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
WB
Western blot
analysis using PPM1A antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
PP2Calpha
PP2C-ALPHA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
WB
Western blot
analysis using PPM1A antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
PP2Calpha
PP2C-ALPHA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
WB
Western blot
analysis using PPM1A antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
PP2Calpha
PP2C-ALPHA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
WB
Western blot
analysis using PPM1A antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
PP2Calpha
PP2C-ALPHA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
WB
Western blot
analysis using PPM1A antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
PP2Calpha
PP2C-ALPHA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
WB
Western blot
analysis using PPM1A antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PPM1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPM1A
Gene Synonyms
PP2CA
Gene Full Name
protein phosphatase, Mg2+/Mn2+ dependent
1A
Gene Summary
The protein encoded by this gene is a
member of the PP2C family of Ser/Thr protein phosphatases. PP2C family
members are known to be negative regulators of cell stress response pathways.
This phosphatase dephosphorylates, and negatively regulates the activities
of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the
activation of p38 and JNK kinase cascades induced by environmental stresses.
This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus
may be involved in cell cycle control. Overexpression of this phosphatase is
reported to activate the expression of the tumor suppressor gene TP53/p53,
which leads to G2/M cell cycle arrest and apoptosis. Three alternatively
spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
42KD，51KD
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
PP2Calpha
PP2C-ALPHA
·
WB
Western blot analysis using PPM1A antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PPM1A antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using PPM1A antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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