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Product Profile

Product Name	Anti-PPP2R4 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHC
	IHC:1:200-1:2000
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	PTPA
Gene Synonyms	PP2A PR53 PPP2R4
Gene Full Name	protein phosphatase 2 phosphatase activator
Gene Summary	Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	40KD
Cellular Localizatio	Cytoplasm, Nucleus

Application

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IHC

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using PPP2R4 antibody with DAB staining.

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IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using PPP2R4 antibody with DAB staining.

Application Notes

IHC:1:200-1:2000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.