|
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
HEL-S-2
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
· 
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB
staining.
· 
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
HEL-S-2
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
HEL-S-2
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
HEL-S-2
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
HEL-S-2
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
HEL-S-2
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
HEL-S-2
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
HEL-S-2
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
HEL-S-2
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CST3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CST3
Gene Synonyms
ARMD11
Gene Full Name
cystatin C
Gene Summary
he cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps
never acquired this inhibitory activity. There are three inhibitory families
in the superfamily, including the type 1 cystatins (stefins), type 2
cystatins and the kininogens. The type 2 cystatin proteins are a class of
cysteine proteinase inhibitors found in a variety of human fluids and
secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and
pseudogenes. This gene is located in the cystatin locus and encodes the most
abundant extracellular inhibitor of cysteine proteases, which is found in
high concentrations in biological fluids and is expressed in virtually all
organs of the body. A mutation in this gene has been associated with amyloid
angiopathy. Expression of this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and aneurysmal aortic lesions,
establishing its role in vascular disease. In addition, this protein has been
shown to have an antimicrobial function, inhibiting the replication of herpes
simplex virus. Alternative splicing results in multiple transcript variants
encoding a single protein. [provided by RefSeq, Nov 2014]
Hide
Molecular
Weight(MW)
16KD
Cellular
Localizatio
Amyloid, Secreted
Application
ICC/IF:1:100-1:500
HEL-S-2
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using CST3 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded thyroid carcinoma tissues using CST3 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using CST3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
IHC:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
-
如何选择适合您实验需求的小鼠整合素β3(ITGB3)酶联免疫试剂盒？ 在进行涉及小鼠整合素β3（ITGB3）的研究时，选择合适的酶联免疫吸附测定（ELISA）试剂盒至关重要。这不仅影响到实验结果的准确性，还关系到研究效率和成本效益。以下是选择适合您实验需求的... VIEW DETAILS
-
鸡抗磷壁酸抗体(TA)ELISA试剂盒现货供应 鸡抗磷壁酸抗体(TA)ELISA试剂盒现货供应 量大价优 鸡抗磷壁酸抗体(TA)ELISA试剂盒是一种专为检测鸡血清、血浆及其他生物样本中抗磷壁酸抗体水平而设计的酶联免疫吸附测定(ELISA)工具... VIEW DETAILS
-
中秋迎好礼 中秋迎好礼 随着国产3A大作《黑神话：悟空》的面世，现我司推出活动。 从即日起至2024年9月18日，购买ELISA试剂盒满五盒，即可申领《黑神话：悟空》数字标准版兑换码。 ... VIEW DETAILS
-
化学实验室守则小分享 一、实验前 在进行化学实验前，学生必须完成预习工作，了解实验的目的、步骤和注意事项。进入实验室前，应穿着适当的防护装备，如实验服、护目镜、实验手套等。此外，学生应提... VIEW DETAILS
- 手机：15214367449
- Q Q：
