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Product Profile

Product Name	Anti-GJC2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	GJC2
Gene Synonyms	Cx47 HLD2 GJA12 SPG44 CX46.6 LMPH1C LMPHM3 PMLDAR More
Gene Full Name	gap junction protein gamma 2
Gene Summary	This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. More
Molecular Weight(MW)	47 kDa
Cellular Localizatio	Cell junction, Cell membrane, Gap junction, Membrane

Application

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WB

Western blot analysis using GJC2 antibody against HEK293(1),MCF-7(2) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using GJC2 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of MG-63 cells using GJC2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.