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Product Profile

Product Name	Anti- CDCA8 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	CDCA8
Gene Synonyms	BOR DasraB MESRGP BOREALIN Hide
Gene Full Name	cell division cycle associated 8
Gene Summary	This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16. Hide
Molecular Weight(MW)	31 kDa
Cellular Localizatio	Centromere, Chromosome, Cytoplasm, Cytoskeleton, Nucleus

Application

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WB

Western blot analysis using CDCA8 antibody against PANC-1(1), MCF-7(2) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using CDCA8 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of MG-63 cells using CDCA8 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.