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      产品展厅
      Anti-LXR alpha antibody
      • 品牌:OminimAbs
      • 产地:上海
      • 型号:毫升
      • 货号:OM641708
      • 发布日期: 2024-09-02
      • 更新日期: 2024-10-09
      产品详请
      产地 上海
      品牌 OminimAbs
      保存条件
      货号 OM641708
      用途 实验研究
      应用范围 科研实验
      抗原来源 电询
      保质期 2年
      抗体名 电询
      是否单克隆
      克隆性
      靶点 电询
      适应物种 电询
      形态 电询
      宿主 电询
      标记物 电询
      包装规格 毫升
      亚型 电询
      标识物 电询
      浓度 电询%
      免疫原 电询
      是否进口

      Product Profile

      Product Name

      Anti-LXR alpha antibody

      Antibody Type

      Primary Antibodies

      Immunogen

      Polypeptide

      Key Feature

      Clonality

      Polyclonal

      Isotype

      IgG

      Host Species

      Rabbit

      Tested Application

      ELISAICC/IFIHCWB

      WB:1:200-1:2000
      IHC:1:200-1:1000
      ICC/IF:1:100-1:500

      Species Reactivity

      HumanMouseRat

      Concentration

      1 mg/ml

      Purification

      Protein A

      Target Information

      Gene Symbol

      NR1H3

      Gene Synonyms

      LXRA
      LXR-a
      RLD-1

      Gene Full Name

      nuclear receptor subfamily 1 group H member 3

      Gene Summary

      The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

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      Molecular Weight(MW)

      50 kDa

      Cellular Localizatio

      Cytoplasm, Nucleus

      Application

      ·        

      WB

      Western blot analysis using LXR alpha antibody against A431(1),Raji(2),HepG2(3) cell lysate.

      ·        

      IHC

      Immunohistochemical analysis of paraffin-embedded breast cancer tissues using LXR alpha antibody with DAB staining.

      ·        

      ICC/IF

      Immunofluorescence analysis of SK-OV-3 cells using LXR alpha antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

      Application Notes

      WB:1:200-1:2000
      IHC:1:200-1:1000
      ICC/IF:1:100-1:500

      Additional Information

      Form

      Liquid

      Storage Instruction

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

      Storage Buffer

      Purified antibody in PBS with 0.05% sodium azide.


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