彩神vll官网-追求健康,你我一起成长

  •  
    产品展厅
    Anti-ER-alpha antibody
    • 品牌:OminimAbs
    • 产地:上海
    • 型号:毫升
    • 货号:OM642132
    • 发布日期: 2024-08-28
    • 更新日期: 2024-10-09
    产品详请
    产地 上海
    品牌 OminimAbs
    保存条件
    货号 OM642132
    用途 实验研究
    应用范围 科研实验
    抗原来源 电询
    保质期 2年
    抗体名 电询
    是否单克隆
    克隆性
    靶点 电询
    适应物种 电询
    形态 电询
    宿主 电询
    标记物 电询
    包装规格 毫升
    亚型 电询
    标识物 电询
    浓度 电询%
    免疫原 电询
    是否进口

    Product Profile

    Product Name

    Anti-ER-alpha antibody

    Antibody Type

    Primary Antibodies

    Immunogen

    Polypeptide

    Key Feature

    Clonality

    Polyclonal

    Isotype

    IgG

    Host Species

    Rabbit

    Tested Application

    ELISAICC/IFIHCWB

    WB:1:200-1:2000
    IHC:1:200-1:1000
    ICC/IF:1:100-1:500

    Species Reactivity

    HumanMouseRat

    Concentration

    1 mg/ml

    Purification

    Protein A

    Target Information

    Gene Symbol

    ESR1

    Gene Synonyms

    ER
    ESR
    Era
    ESRA
    ESTRR
    NR3A1

    Hide 

    Gene Full Name

    estrogen receptor 1

    Gene Summary

    This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020]

    Hide 

    Molecular Weight(MW)

    66 kDa

    Source

    Rabbit

    Cellular Localizatio

    Nucleus. Cytoplasm. Cell membrane.

    Application

    ·        

    WB

    Western blot analysis using ER alpha antibody against Raji(1), Jurkat(2), HepG2(3) cell lysate.

    ·        

    IHC

    Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using ER alpha antibody with DAB staining.

    ·        

    ICC/IF

    Immunofluorescence analysis of MG-63 cells using ER alpha antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

    Application Notes

    WB:1:200-1:2000
    IHC:1:200-1:1000
    ICC/IF:1:100-1:500

    Additional Information

    Form

    Liquid

    Storage Instruction

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

    Storage Buffer

    Purified antibody in PBS with 0.05% sodium azide.


    新闻资讯
    联系方式
    手机:15214367449
    Q Q:
    微信扫一扫
    【网站地图】【sitemap】