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Product Profile

Product Name	Anti-CCR2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	CCR2
Gene Synonyms	CKR2 CCR-2 CCR2A CCR2B CD192 CKR2A CKR2B CMKBR2 MCP-1-R CC-CKR-2 Hide
Gene Full Name	C-C motif chemokine receptor 2
Gene Summary	The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017] Hide
Molecular Weight(MW)	42 kDa
Source	Rabbit
Cellular Localizatio	Cell membrane

Application

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WB

Western blot analysis using CCR2 antibody against A549 (1), HepG2 (2) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using CCR2 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of NIH3T3 cells using CCR2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.