|
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | 电询 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-HAS2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HAS2
Gene Full Name
hyaluronan synthase 2
Gene Summary
Hyaluronan or hyaluronic acid (HA) is a
high molecular weight unbranched polysaccharide synthesized by a wide variety
of organisms from bacteria to mammals, and is a constituent of the
extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine
residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is
synthesized by membrane-bound synthase at the inner surface of the plasma
membrane, and the chains are extruded through pore-like structures into the
extracellular space. It serves a variety of functions, including space
filling, lubrication of joints, and provision of a matrix through which cells
can migrate. HA is actively produced during wound healing and tissue repair
to provide a framework for ingrowth of blood vessels and fibroblasts. Changes
in the serum concentration of HA are associated with inflammatory and
degenerative arthropathies such as rheumatoid arthritis. In addition, the
interaction of HA with the leukocyte receptor CD44 is important in tissue-specific
homing by leukocytes, and overexpression of HA receptors has been correlated
with tumor metastasis. HAS2 is a member of the newly identified vertebrate
gene family encoding putative hyaluronan synthases, and its amino acid
sequence shows significant homology to glycosaminoglycan synthetase (DG42)
from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by
RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
64 kDa（Observed:110
kDa）
Source
Rabbit
Cellular
Localizatio
Membrane
Application
·
WB
Western blot
analysis using HAS2 antibody against HEK293 (1), A549 (2) cell lysate.
· 
ICC/IF
Immunofluorescence
analysis of NIH3T3 cells using HAS2 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HAS2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HAS2
Gene Full Name
hyaluronan synthase 2
Gene Summary
Hyaluronan or hyaluronic acid (HA) is a
high molecular weight unbranched polysaccharide synthesized by a wide variety
of organisms from bacteria to mammals, and is a constituent of the
extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine
residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is
synthesized by membrane-bound synthase at the inner surface of the plasma
membrane, and the chains are extruded through pore-like structures into the
extracellular space. It serves a variety of functions, including space
filling, lubrication of joints, and provision of a matrix through which cells
can migrate. HA is actively produced during wound healing and tissue repair
to provide a framework for ingrowth of blood vessels and fibroblasts. Changes
in the serum concentration of HA are associated with inflammatory and
degenerative arthropathies such as rheumatoid arthritis. In addition, the
interaction of HA with the leukocyte receptor CD44 is important in tissue-specific
homing by leukocytes, and overexpression of HA receptors has been correlated
with tumor metastasis. HAS2 is a member of the newly identified vertebrate
gene family encoding putative hyaluronan synthases, and its amino acid
sequence shows significant homology to glycosaminoglycan synthetase (DG42)
from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by
RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
64 kDa（Observed:110
kDa）
Source
Rabbit
Cellular
Localizatio
Membrane
Application
·
WB
Western blot
analysis using HAS2 antibody against HEK293 (1), A549 (2) cell lysate.
·
ICC/IF
Immunofluorescence
analysis of NIH3T3 cells using HAS2 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HAS2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HAS2
Gene Full Name
hyaluronan synthase 2
Gene Summary
Hyaluronan or hyaluronic acid (HA) is a
high molecular weight unbranched polysaccharide synthesized by a wide variety
of organisms from bacteria to mammals, and is a constituent of the
extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine
residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is
synthesized by membrane-bound synthase at the inner surface of the plasma
membrane, and the chains are extruded through pore-like structures into the
extracellular space. It serves a variety of functions, including space
filling, lubrication of joints, and provision of a matrix through which cells
can migrate. HA is actively produced during wound healing and tissue repair
to provide a framework for ingrowth of blood vessels and fibroblasts. Changes
in the serum concentration of HA are associated with inflammatory and
degenerative arthropathies such as rheumatoid arthritis. In addition, the
interaction of HA with the leukocyte receptor CD44 is important in tissue-specific
homing by leukocytes, and overexpression of HA receptors has been correlated
with tumor metastasis. HAS2 is a member of the newly identified vertebrate
gene family encoding putative hyaluronan synthases, and its amino acid
sequence shows significant homology to glycosaminoglycan synthetase (DG42)
from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by
RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
64 kDa（Observed:110
kDa）
Source
Rabbit
Cellular
Localizatio
Membrane
Application
·
WB
Western blot
analysis using HAS2 antibody against HEK293 (1), A549 (2) cell lysate.
·
ICC/IF
Immunofluorescence
analysis of NIH3T3 cells using HAS2 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HAS2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HAS2
Gene Full Name
hyaluronan synthase 2
Gene Summary
Hyaluronan or hyaluronic acid (HA) is a
high molecular weight unbranched polysaccharide synthesized by a wide variety
of organisms from bacteria to mammals, and is a constituent of the
extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine
residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is
synthesized by membrane-bound synthase at the inner surface of the plasma
membrane, and the chains are extruded through pore-like structures into the
extracellular space. It serves a variety of functions, including space
filling, lubrication of joints, and provision of a matrix through which cells
can migrate. HA is actively produced during wound healing and tissue repair
to provide a framework for ingrowth of blood vessels and fibroblasts. Changes
in the serum concentration of HA are associated with inflammatory and
degenerative arthropathies such as rheumatoid arthritis. In addition, the
interaction of HA with the leukocyte receptor CD44 is important in tissue-specific
homing by leukocytes, and overexpression of HA receptors has been correlated
with tumor metastasis. HAS2 is a member of the newly identified vertebrate
gene family encoding putative hyaluronan synthases, and its amino acid
sequence shows significant homology to glycosaminoglycan synthetase (DG42)
from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by
RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
64 kDa（Observed:110
kDa）
Source
Rabbit
Cellular
Localizatio
Membrane
Application
·
WB
Western blot
analysis using HAS2 antibody against HEK293 (1), A549 (2) cell lysate.
·
ICC/IF
Immunofluorescence
analysis of NIH3T3 cells using HAS2 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HAS2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HAS2
Gene Full Name
hyaluronan synthase 2
Gene Summary
Hyaluronan or hyaluronic acid (HA) is a
high molecular weight unbranched polysaccharide synthesized by a wide variety
of organisms from bacteria to mammals, and is a constituent of the
extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine
residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is
synthesized by membrane-bound synthase at the inner surface of the plasma
membrane, and the chains are extruded through pore-like structures into the
extracellular space. It serves a variety of functions, including space
filling, lubrication of joints, and provision of a matrix through which cells
can migrate. HA is actively produced during wound healing and tissue repair
to provide a framework for ingrowth of blood vessels and fibroblasts. Changes
in the serum concentration of HA are associated with inflammatory and
degenerative arthropathies such as rheumatoid arthritis. In addition, the
interaction of HA with the leukocyte receptor CD44 is important in tissue-specific
homing by leukocytes, and overexpression of HA receptors has been correlated
with tumor metastasis. HAS2 is a member of the newly identified vertebrate
gene family encoding putative hyaluronan synthases, and its amino acid
sequence shows significant homology to glycosaminoglycan synthetase (DG42)
from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by
RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
64 kDa（Observed:110
kDa）
Source
Rabbit
Cellular
Localizatio
Membrane
Application
ICC/IF:1:100-1:500
·
WB
Western blot analysis using HAS2 antibody against HEK293 (1), A549 (2) cell lysate.
·
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using HAS2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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