Product Profile

Product Name	Anti-TGFB3 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	TGFB3
Gene Synonyms	ARVD LDS5 RNHF ARVD1 TGF-beta3 Hide
Gene Full Name	transforming growth factor beta 3
Gene Summary	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016] Hide
Molecular Weight(MW)	47 KDa
Source	Rabbit
Cellular Localizatio	Secreted

Application

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WB

Western blot analysis using TGFB3 antibody against NIH 3T3 (1), PC-12 (2), Hela (3), HEK 293 (4), Hep G2 (5) cell lysate.

·        

IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using TGFB3 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of Huvec cells using TGFB3 antibody (green). Blue: DAPI fluorescent DNA dye.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.