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产品展厅
Anti-CyclinA antibody
  • 品牌:OminimAbs
  • 产地:上海
  • 型号:毫升
  • 货号:电询
  • 发布日期: 2024-08-16
  • 更新日期: 2024-10-09
产品详请
产地 上海
品牌 OminimAbs
保存条件
货号 电询
用途 实验研究
应用范围 科研实验
抗原来源 电询
保质期 2年
抗体名 电询
是否单克隆
克隆性
靶点 电询
适应物种 电询
形态 电询
宿主 电询
标记物 电询
包装规格 毫升
亚型 电询
标识物 电询
浓度 电询%
免疫原 电询
是否进口

Product Profile

Product Name

Anti-CyclinA antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Key Feature

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAICC/IFIHCWB

WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Species Reactivity

HumanMouseRat

Concentration

1 mg/ml

Purification

Protein A

Target Information

Gene Symbol

CCNA1

Gene Synonyms

CT146

Gene Full Name

cyclin A1

Gene Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Molecular Weight(MW)

49 kDa

Source

Rabbit

Cellular Localizatio

Nucleus

Application

·        

WB

Western blot analysis using CyclinA antibody against A549 (1) cell lysate.

·        

IHC

Immunohistochemical analysis of paraffin-embedded laryngeal cancer tissues using CyclinA antibody with DAB staining.

·        

ICC/IF

Immunofluorescence analysis of HepG2 cells using CyclinA antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Additional Information

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.


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