|
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-IL4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
IL4
Gene Synonyms
BSF1
IL-4
BCGF1
BSF-1
BCGF-1
Hide
Gene Full Name
interleukin 4
Gene Summary
The protein encoded by this gene is a
pleiotropic cytokine produced by activated T cells. This cytokine is a ligand
for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13,
which may contribute to many overlapping functions of this cytokine and IL13.
STAT6, a signal transducer and activator of transcription, has been shown to
play a central role in mediating the immune regulatory signal of this
cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on
chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and
IL5 are found to be regulated coordinately by several long-range regulatory
elements in an over 120 kilobase range on the chromosome. IL4 is considered
an important cytokine for tissue repair, counterbalancing the effects of
proinflammatory type 1 cytokines, however, it also promotes allergic airway
inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a
variety of human host responses such as allergic, anti-parasitic, wound healing,
and acute inflammation. This cytokine has been reported to promote resolution
of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has
an essential role in the production of allergen-specific immunoglobin (Ig) E.
This pro-inflammatory cytokine has been observed to be increased in COVID-19
(Coronavirus disease 2019) patients, but is not necessarily associated with
severe COVID-19 pathology. Two alternatively spliced transcript variants of
this gene encoding distinct isoforms have been reported. [provided by RefSeq,
Aug 2020]
Hide
Molecular
Weight(MW)
17 kDa
Source
Rabbit
Cellular
Localizatio
Secreted
Application
·
WB
Western blot
analysis using IL4 antibody against Jurkat (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded stomach cancer tissues using IL4 antibody with
DAB staining
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using IL4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-IL4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
IL4
Gene Synonyms
BSF1
IL-4
BCGF1
BSF-1
BCGF-1
Hide
Gene Full Name
interleukin 4
Gene Summary
The protein encoded by this gene is a
pleiotropic cytokine produced by activated T cells. This cytokine is a ligand
for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13,
which may contribute to many overlapping functions of this cytokine and IL13.
STAT6, a signal transducer and activator of transcription, has been shown to
play a central role in mediating the immune regulatory signal of this
cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on
chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and
IL5 are found to be regulated coordinately by several long-range regulatory
elements in an over 120 kilobase range on the chromosome. IL4 is considered
an important cytokine for tissue repair, counterbalancing the effects of
proinflammatory type 1 cytokines, however, it also promotes allergic airway
inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a
variety of human host responses such as allergic, anti-parasitic, wound healing,
and acute inflammation. This cytokine has been reported to promote resolution
of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has
an essential role in the production of allergen-specific immunoglobin (Ig) E.
This pro-inflammatory cytokine has been observed to be increased in COVID-19
(Coronavirus disease 2019) patients, but is not necessarily associated with
severe COVID-19 pathology. Two alternatively spliced transcript variants of
this gene encoding distinct isoforms have been reported. [provided by RefSeq,
Aug 2020]
Hide
Molecular
Weight(MW)
17 kDa
Source
Rabbit
Cellular
Localizatio
Secreted
Application
·
WB
Western blot
analysis using IL4 antibody against Jurkat (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded stomach cancer tissues using IL4 antibody with
DAB staining
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using IL4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-IL4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
IL4
Gene Synonyms
BSF1
IL-4
BCGF1
BSF-1
BCGF-1
Hide
Gene Full Name
interleukin 4
Gene Summary
The protein encoded by this gene is a
pleiotropic cytokine produced by activated T cells. This cytokine is a ligand
for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13,
which may contribute to many overlapping functions of this cytokine and IL13.
STAT6, a signal transducer and activator of transcription, has been shown to
play a central role in mediating the immune regulatory signal of this
cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on
chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and
IL5 are found to be regulated coordinately by several long-range regulatory
elements in an over 120 kilobase range on the chromosome. IL4 is considered
an important cytokine for tissue repair, counterbalancing the effects of
proinflammatory type 1 cytokines, however, it also promotes allergic airway
inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a
variety of human host responses such as allergic, anti-parasitic, wound healing,
and acute inflammation. This cytokine has been reported to promote resolution
of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has
an essential role in the production of allergen-specific immunoglobin (Ig) E.
This pro-inflammatory cytokine has been observed to be increased in COVID-19
(Coronavirus disease 2019) patients, but is not necessarily associated with
severe COVID-19 pathology. Two alternatively spliced transcript variants of
this gene encoding distinct isoforms have been reported. [provided by RefSeq,
Aug 2020]
Hide
Molecular
Weight(MW)
17 kDa
Source
Rabbit
Cellular
Localizatio
Secreted
Application
·
WB
Western blot
analysis using IL4 antibody against Jurkat (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded stomach cancer tissues using IL4 antibody with
DAB staining
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using IL4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-IL4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
IL4
Gene Synonyms
BSF1
IL-4
BCGF1
BSF-1
BCGF-1
Hide
Gene Full Name
interleukin 4
Gene Summary
The protein encoded by this gene is a
pleiotropic cytokine produced by activated T cells. This cytokine is a ligand
for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13,
which may contribute to many overlapping functions of this cytokine and IL13.
STAT6, a signal transducer and activator of transcription, has been shown to
play a central role in mediating the immune regulatory signal of this
cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on
chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and
IL5 are found to be regulated coordinately by several long-range regulatory
elements in an over 120 kilobase range on the chromosome. IL4 is considered
an important cytokine for tissue repair, counterbalancing the effects of
proinflammatory type 1 cytokines, however, it also promotes allergic airway
inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a
variety of human host responses such as allergic, anti-parasitic, wound healing,
and acute inflammation. This cytokine has been reported to promote resolution
of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has
an essential role in the production of allergen-specific immunoglobin (Ig) E.
This pro-inflammatory cytokine has been observed to be increased in COVID-19
(Coronavirus disease 2019) patients, but is not necessarily associated with
severe COVID-19 pathology. Two alternatively spliced transcript variants of
this gene encoding distinct isoforms have been reported. [provided by RefSeq,
Aug 2020]
Hide
Molecular
Weight(MW)
17 kDa
Source
Rabbit
Cellular
Localizatio
Secreted
Application
·
WB
Western blot
analysis using IL4 antibody against Jurkat (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded stomach cancer tissues using IL4 antibody with
DAB staining
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using IL4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-IL4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
IL4
Gene Synonyms
BSF1
IL-4
BCGF1
BSF-1
BCGF-1
Hide
Gene Full Name
interleukin 4
Gene Summary
The protein encoded by this gene is a
pleiotropic cytokine produced by activated T cells. This cytokine is a ligand
for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13,
which may contribute to many overlapping functions of this cytokine and IL13.
STAT6, a signal transducer and activator of transcription, has been shown to
play a central role in mediating the immune regulatory signal of this
cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on
chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and
IL5 are found to be regulated coordinately by several long-range regulatory
elements in an over 120 kilobase range on the chromosome. IL4 is considered
an important cytokine for tissue repair, counterbalancing the effects of
proinflammatory type 1 cytokines, however, it also promotes allergic airway
inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a
variety of human host responses such as allergic, anti-parasitic, wound healing,
and acute inflammation. This cytokine has been reported to promote resolution
of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has
an essential role in the production of allergen-specific immunoglobin (Ig) E.
This pro-inflammatory cytokine has been observed to be increased in COVID-19
(Coronavirus disease 2019) patients, but is not necessarily associated with
severe COVID-19 pathology. Two alternatively spliced transcript variants of
this gene encoding distinct isoforms have been reported. [provided by RefSeq,
Aug 2020]
Hide
Molecular
Weight(MW)
17 kDa
Source
Rabbit
Cellular
Localizatio
Secreted
Application
·
WB
Western blot
analysis using IL4 antibody against Jurkat (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded stomach cancer tissues using IL4 antibody with
DAB staining
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using IL4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-IL4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
IL4
Gene Synonyms
BSF1
IL-4
BCGF1
BSF-1
BCGF-1
Hide
Gene Full Name
interleukin 4
Gene Summary
The protein encoded by this gene is a
pleiotropic cytokine produced by activated T cells. This cytokine is a ligand
for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13,
which may contribute to many overlapping functions of this cytokine and IL13.
STAT6, a signal transducer and activator of transcription, has been shown to
play a central role in mediating the immune regulatory signal of this
cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on
chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and
IL5 are found to be regulated coordinately by several long-range regulatory
elements in an over 120 kilobase range on the chromosome. IL4 is considered
an important cytokine for tissue repair, counterbalancing the effects of
proinflammatory type 1 cytokines, however, it also promotes allergic airway
inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a
variety of human host responses such as allergic, anti-parasitic, wound healing,
and acute inflammation. This cytokine has been reported to promote resolution
of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has
an essential role in the production of allergen-specific immunoglobin (Ig) E.
This pro-inflammatory cytokine has been observed to be increased in COVID-19
(Coronavirus disease 2019) patients, but is not necessarily associated with
severe COVID-19 pathology. Two alternatively spliced transcript variants of
this gene encoding distinct isoforms have been reported. [provided by RefSeq,
Aug 2020]
Hide
Molecular
Weight(MW)
17 kDa
Source
Rabbit
Cellular
Localizatio
Secreted
Application
·
WB
Western blot
analysis using IL4 antibody against Jurkat (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded stomach cancer tissues using IL4 antibody with
DAB staining
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using IL4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
|
Product Name |
Anti-IL4 antibody |
|
Antibody Type |
Primary Antibodies |
|
Immunogen |
Polypeptide |
Key Feature
|
Clonality |
Polyclonal |
|
Isotype |
IgG |
|
Host Species |
Rabbit |
|
Tested Application |
ELISAICC/IFIHCWB |
|
WB:1:200-1:2000 |
|
|
Species Reactivity |
HumanMouseRat |
|
Concentration |
1 mg/ml |
|
Purification |
Protein A |
Target Information
|
Gene Symbol |
IL4 |
|
Gene Synonyms |
BSF1 Hide |
|
Gene Full Name |
interleukin 4 |
|
Gene Summary |
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation. This cytokine has been reported to promote resolution of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has an essential role in the production of allergen-specific immunoglobin (Ig) E. This pro-inflammatory cytokine has been observed to be increased in COVID-19 (Coronavirus disease 2019) patients, but is not necessarily associated with severe COVID-19 pathology. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020] Hide |
|
Molecular Weight(MW) |
17 kDa |
|
Source |
Rabbit |
|
Cellular Localizatio |
Secreted |
Application
·
WB
Western blot analysis using IL4 antibody against Jurkat (1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using IL4 antibody with DAB staining
·
ICC/IF
Immunofluorescence analysis of SK-OV-3 cells using IL4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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