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Product Profile

Product Name	Anti-GluR1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFWB
	WB:1:200-1:2000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	GRIA1
Gene Synonyms	GLUH1 GLUR1 GLURA GluA1 HBGR1 Hide
Gene Full Name	glutamate ionotropic receptor AMPA type subunit 1
Gene Summary	Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	102 kDa
Source	Rabbit
Cellular Localizatio	Cell membrane. Endoplasmic reticulum membrane. Cell junction > synapse > postsynaptic cell membrane

Application

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WB

Western blot analysis using GluR1 antibody against Caco-2 (1), COS-7 (2), HT1080 (3) cell lysate.

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ICC/IF

Immunofluorescence analysis of HEK293 cells using GluR1 antibody(green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.