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Product Profile

Product Name	Anti-ESR2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000
Species Reactivity	GoatHumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	ESR2
Gene Synonyms	Erb ESRB ODG8 ESTRB NR3A2 ER-BETA ESR-BETA Hide
Gene Full Name	estrogen receptor 2
Gene Summary	This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	59 kDa
Source	Rabbit
Cellular Localizatio	Nucleus.

Application

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WB

Western blot analysis using ESR2 antibody against HT1080 (1), MG-63 (2), PC-12 (3) cell lysate.

·        

IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using ESR2 antibody with DAB staining.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.