|
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-Smad2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SMAD2
Gene Synonyms
JV18
MADH2
MADR2
JV18-1
hMAD-2
hSMAD2
More
Gene Full Name
SMAD family member 2
Gene Summary
The protein encoded by this gene belongs
to the SMAD, a family of proteins similar to the gene products of the
Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans
gene Sma. SMAD proteins are signal transducers and transcriptional modulators
that mediate multiple signaling pathways. This protein mediates the signal of
the transforming growth factor (TGF)-beta, and thus regulates multiple
cellular processes, such as cell proliferation, apoptosis, and
differentiation. This protein is recruited to the TGF-beta receptors through
its interaction with the SMAD anchor for receptor activation (SARA) protein.
In response to TGF-beta signal, this protein is phosphorylated by the
TGF-beta receptors. The phosphorylation induces the dissociation of this
protein with SARA and the association with the family member SMAD4. The
association with SMAD4 is important for the translocation of this protein
into the nucleus, where it binds to target promoters and forms a
transcription repressor complex with other cofactors. This protein can also
be phosphorylated by activin type 1 receptor kinase, and mediates the signal
from the activin. Alternatively spliced transcript variants have been
observed for this gene. [provided by RefSeq, May 2012]
More
Source
Rabbit
Cellular
Localizatio
Cytoplasm. Nucleus.
Application
· 
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using Smad2 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using Smad2 antibody(green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-Smad2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SMAD2
Gene Synonyms
JV18
MADH2
MADR2
JV18-1
hMAD-2
hSMAD2
More
Gene Full Name
SMAD family member 2
Gene Summary
The protein encoded by this gene belongs
to the SMAD, a family of proteins similar to the gene products of the
Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans
gene Sma. SMAD proteins are signal transducers and transcriptional modulators
that mediate multiple signaling pathways. This protein mediates the signal of
the transforming growth factor (TGF)-beta, and thus regulates multiple
cellular processes, such as cell proliferation, apoptosis, and
differentiation. This protein is recruited to the TGF-beta receptors through
its interaction with the SMAD anchor for receptor activation (SARA) protein.
In response to TGF-beta signal, this protein is phosphorylated by the
TGF-beta receptors. The phosphorylation induces the dissociation of this
protein with SARA and the association with the family member SMAD4. The
association with SMAD4 is important for the translocation of this protein
into the nucleus, where it binds to target promoters and forms a
transcription repressor complex with other cofactors. This protein can also
be phosphorylated by activin type 1 receptor kinase, and mediates the signal
from the activin. Alternatively spliced transcript variants have been
observed for this gene. [provided by RefSeq, May 2012]
More
Source
Rabbit
Cellular
Localizatio
Cytoplasm. Nucleus.
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using Smad2 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using Smad2 antibody(green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-Smad2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SMAD2
Gene Synonyms
JV18
MADH2
MADR2
JV18-1
hMAD-2
hSMAD2
More
Gene Full Name
SMAD family member 2
Gene Summary
The protein encoded by this gene belongs
to the SMAD, a family of proteins similar to the gene products of the
Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans
gene Sma. SMAD proteins are signal transducers and transcriptional modulators
that mediate multiple signaling pathways. This protein mediates the signal of
the transforming growth factor (TGF)-beta, and thus regulates multiple
cellular processes, such as cell proliferation, apoptosis, and
differentiation. This protein is recruited to the TGF-beta receptors through
its interaction with the SMAD anchor for receptor activation (SARA) protein.
In response to TGF-beta signal, this protein is phosphorylated by the
TGF-beta receptors. The phosphorylation induces the dissociation of this
protein with SARA and the association with the family member SMAD4. The
association with SMAD4 is important for the translocation of this protein
into the nucleus, where it binds to target promoters and forms a
transcription repressor complex with other cofactors. This protein can also
be phosphorylated by activin type 1 receptor kinase, and mediates the signal
from the activin. Alternatively spliced transcript variants have been
observed for this gene. [provided by RefSeq, May 2012]
More
Source
Rabbit
Cellular
Localizatio
Cytoplasm. Nucleus.
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using Smad2 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using Smad2 antibody(green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-Smad2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SMAD2
Gene Synonyms
JV18
MADH2
MADR2
JV18-1
hMAD-2
hSMAD2
More
Gene Full Name
SMAD family member 2
Gene Summary
The protein encoded by this gene belongs
to the SMAD, a family of proteins similar to the gene products of the
Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans
gene Sma. SMAD proteins are signal transducers and transcriptional modulators
that mediate multiple signaling pathways. This protein mediates the signal of
the transforming growth factor (TGF)-beta, and thus regulates multiple
cellular processes, such as cell proliferation, apoptosis, and
differentiation. This protein is recruited to the TGF-beta receptors through
its interaction with the SMAD anchor for receptor activation (SARA) protein.
In response to TGF-beta signal, this protein is phosphorylated by the
TGF-beta receptors. The phosphorylation induces the dissociation of this
protein with SARA and the association with the family member SMAD4. The
association with SMAD4 is important for the translocation of this protein
into the nucleus, where it binds to target promoters and forms a
transcription repressor complex with other cofactors. This protein can also
be phosphorylated by activin type 1 receptor kinase, and mediates the signal
from the activin. Alternatively spliced transcript variants have been
observed for this gene. [provided by RefSeq, May 2012]
More
Source
Rabbit
Cellular
Localizatio
Cytoplasm. Nucleus.
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using Smad2 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using Smad2 antibody(green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-Smad2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SMAD2
Gene Synonyms
JV18
MADH2
MADR2
JV18-1
hMAD-2
hSMAD2
More
Gene Full Name
SMAD family member 2
Gene Summary
The protein encoded by this gene belongs
to the SMAD, a family of proteins similar to the gene products of the
Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans
gene Sma. SMAD proteins are signal transducers and transcriptional modulators
that mediate multiple signaling pathways. This protein mediates the signal of
the transforming growth factor (TGF)-beta, and thus regulates multiple
cellular processes, such as cell proliferation, apoptosis, and
differentiation. This protein is recruited to the TGF-beta receptors through
its interaction with the SMAD anchor for receptor activation (SARA) protein.
In response to TGF-beta signal, this protein is phosphorylated by the
TGF-beta receptors. The phosphorylation induces the dissociation of this
protein with SARA and the association with the family member SMAD4. The
association with SMAD4 is important for the translocation of this protein
into the nucleus, where it binds to target promoters and forms a
transcription repressor complex with other cofactors. This protein can also
be phosphorylated by activin type 1 receptor kinase, and mediates the signal
from the activin. Alternatively spliced transcript variants have been
observed for this gene. [provided by RefSeq, May 2012]
More
Source
Rabbit
Cellular
Localizatio
Cytoplasm. Nucleus.
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using Smad2 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using Smad2 antibody(green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-Smad2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SMAD2
Gene Synonyms
JV18
MADH2
MADR2
JV18-1
hMAD-2
hSMAD2
More
Gene Full Name
SMAD family member 2
Gene Summary
The protein encoded by this gene belongs
to the SMAD, a family of proteins similar to the gene products of the
Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans
gene Sma. SMAD proteins are signal transducers and transcriptional modulators
that mediate multiple signaling pathways. This protein mediates the signal of
the transforming growth factor (TGF)-beta, and thus regulates multiple
cellular processes, such as cell proliferation, apoptosis, and
differentiation. This protein is recruited to the TGF-beta receptors through
its interaction with the SMAD anchor for receptor activation (SARA) protein.
In response to TGF-beta signal, this protein is phosphorylated by the
TGF-beta receptors. The phosphorylation induces the dissociation of this
protein with SARA and the association with the family member SMAD4. The
association with SMAD4 is important for the translocation of this protein
into the nucleus, where it binds to target promoters and forms a
transcription repressor complex with other cofactors. This protein can also
be phosphorylated by activin type 1 receptor kinase, and mediates the signal
from the activin. Alternatively spliced transcript variants have been
observed for this gene. [provided by RefSeq, May 2012]
More
Source
Rabbit
Cellular
Localizatio
Cytoplasm. Nucleus.
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using Smad2 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using Smad2 antibody(green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-Smad2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SMAD2
Gene Synonyms
JV18
MADH2
MADR2
JV18-1
hMAD-2
hSMAD2
More
Gene Full Name
SMAD family member 2
Gene Summary
The protein encoded by this gene belongs
to the SMAD, a family of proteins similar to the gene products of the
Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans
gene Sma. SMAD proteins are signal transducers and transcriptional modulators
that mediate multiple signaling pathways. This protein mediates the signal of
the transforming growth factor (TGF)-beta, and thus regulates multiple
cellular processes, such as cell proliferation, apoptosis, and
differentiation. This protein is recruited to the TGF-beta receptors through
its interaction with the SMAD anchor for receptor activation (SARA) protein.
In response to TGF-beta signal, this protein is phosphorylated by the
TGF-beta receptors. The phosphorylation induces the dissociation of this
protein with SARA and the association with the family member SMAD4. The
association with SMAD4 is important for the translocation of this protein
into the nucleus, where it binds to target promoters and forms a
transcription repressor complex with other cofactors. This protein can also
be phosphorylated by activin type 1 receptor kinase, and mediates the signal
from the activin. Alternatively spliced transcript variants have been
observed for this gene. [provided by RefSeq, May 2012]
More
Source
Rabbit
Cellular
Localizatio
Cytoplasm. Nucleus.
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using Smad2 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using Smad2 antibody(green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Profile
|
Product Name |
Anti-Smad2 antibody |
|
Antibody Type |
Primary Antibodies |
|
Immunogen |
Polypeptide |
Key Feature
|
Clonality |
Polyclonal |
|
Isotype |
IgG |
|
Host Species |
Rabbit |
|
Tested Application |
ELISAICC/IFIHC |
|
IHC:1:200-1:1000 |
|
|
Species Reactivity |
HumanMouseRat |
|
Concentration |
1 mg/ml |
|
Purification |
Protein A |
Target Information
|
Gene Symbol |
SMAD2 |
|
Gene Synonyms |
JV18 More |
|
Gene Full Name |
SMAD family member 2 |
|
Gene Summary |
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] More |
|
Source |
Rabbit |
|
Cellular Localizatio |
Cytoplasm. Nucleus. |
Application
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using Smad2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of SK-OV-3 cells using Smad2 antibody(green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
IHC:1:200-1:1000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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