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    Anti-MCP1 antibody
    • 品牌:OminimAbs
    • 产地:上海
    • 型号:毫升
    • 货号:OM641708
    • 发布日期: 2024-08-15
    • 更新日期: 2024-10-09
    产品详请
    产地 上海
    品牌 OminimAbs
    保存条件
    货号 OM641708
    用途 实验研究
    应用范围 科研实验
    抗原来源 电询
    保质期 2年
    抗体名 电询
    是否单克隆
    克隆性
    靶点 电询
    适应物种 电询
    形态 电询
    宿主 电询
    标记物 电询
    包装规格 毫升
    亚型 电询
    标识物 电询
    浓度 电询%
    免疫原 电询
    是否进口

    Product Profile

    Product Name

    Anti-MCP1 antibody

    Antibody Type

    Primary Antibodies

    Immunogen

    Polypeptide

    Key Feature

    Clonality

    Polyclonal

    Isotype

    IgG

    Host Species

    Rabbit

    Tested Application

    ELISAICC/IFWB

    WB:1:200-1:2000
    ICC/IF:1:100-1:500

    Species Reactivity

    HumanMouseRat

    Concentration

    1 mg/ml

    Purification

    Protein A

    Target Information

    Gene Symbol

    CCL2

    Gene Synonyms

    HC11
    MCAF
    MCP1
    MCP-1
    SCYA2
    GDCF-2
    SMC-CF
    HSMCR30

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    Gene Full Name

    C-C motif chemokine ligand 2

    Gene Summary

    This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARSCoV2) infection. [provided by RefSeq, Aug 2020]

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    Molecular Weight(MW)

    11 kDa

    Source

    Rabbit

    Cellular Localizatio

    Extracellular region or secreted

    Application

    ·        

    WB

    Western blot analysis using MCP1 antibody against HepG2 (1),B16 (2) cell lysate.

    ·        

    ICC/IF

    Immunofluorescence analysis of Hela cells using MCP1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

    Application Notes

    WB:1:200-1:2000
    ICC/IF:1:100-1:500

    Additional Information

    Form

    Liquid

    Storage Instruction

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

    Storage Buffer

    Purified antibody in PBS with 0.05% sodium azide.


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