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    Anti-PGC1 alpha antibody
    • 品牌:OminimAbs
    • 产地:上海
    • 型号:毫升
    • 货号:OM641708
    • 发布日期: 2024-08-14
    • 更新日期: 2024-10-09
    产品详请
    产地 上海
    品牌 OminimAbs
    保存条件
    货号 OM641708
    用途 实验研究
    应用范围 科研实验
    抗原来源 电询
    保质期 2年
    抗体名 电询
    是否单克隆
    克隆性
    靶点 电询
    适应物种 电询
    形态 电询
    宿主 电询
    标记物 电询
    包装规格 毫升
    亚型 电询
    标识物 电询
    浓度 电询%
    免疫原 电询
    是否进口


    Product Profile

    Product Name

    Anti-PGC1 alpha antibody

    Antibody Type

    Primary Antibodies

    Immunogen

    Polypeptide

    Key Feature

    Clonality

    Polyclonal

    Isotype

    IgG

    Host Species

    Rabbit

    Tested Application

    ELISAICC/IFIHCWB

    WB:1:200-1:2000
    IHC:1:200-1:1000
    ICC/IF:1:100-1:500

    Species Reactivity

    HumanMouseRat

    Concentration

    1 mg/ml

    Purification

    Protein A

    Target Information

    Gene Symbol

    PPARGC1A

    Gene Synonyms

    LEM6
    PGC1
    PGC1A
    PGC-1v
    PPARGC1
    PGC-1alpha
    PGC-1(alpha)

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    Gene Full Name

    PPARG coactivator 1 alpha

    Gene Summary

    The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]

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    Molecular Weight(MW)

    91 kDa

    Source

    Rabbit

    Cellular Localizatio

    Cytoplasm. Nucleus; Nucleus and Nucleus. Nucleus; PML body

    Application

    ·          

    WB

    Western blot analysis using PGC1 antibody against Hep PC-12 (1) cell lysate.

    ·          

    IHC

    Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PGC1 antibody with DAB staining.

    ·          

    ICC/IF

    Immunofluorescence analysis of Hela cells using PGC1 alpha antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

    Application Notes

    WB:1:200-1:2000
    IHC:1:200-1:1000
    ICC/IF:1:100-1:500

    Additional Information

    Form

    Liquid

    Storage Instruction

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

    Storage Buffer

    Purified antibody in PBS with 0.05% sodium azide.

     

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