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Product Name

Anti-TGF beta1 antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAIHCWB

WB:1:200-1:2000
IHC:1:200-1:1000

Species Reactivity

GoatHumanMouseRat

Concentration

1mg/ml

Purification

Protein A

Gene Symbol

TGFB1

Gene Synonyms

CED
LAP
DPD1
TGFB
IBDIMDE
TGFbeta
TGF-beta1

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Gene Full Name

transforming growth factor beta 1

Gene Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]

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Molecular Weight(

44 kDa（Observed:53 kDa）

Cellular Localizatio

Extracellular region or secreted

Application Notes

WB:1:200-1:2000
IHC:1:200-1:1000

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide